1. Metabolic Enzyme/Protease
  2. Aldehyde Dehydrogenase (ALDH)

Aldehyde Dehydrogenase (ALDH)

Aldehyde dehydrogenase 1 (ALDH1), which is a putative marker of breast cancer stem cells (CSCs), in triple negative breast cancer (TNBC) tissues.

Mitochondrial aldehyde dehydrogenase (ALDH2) is a member of the 19-strong human aldehyde dehydrogenase family of NADP+-dependent enzymes.

ALDH2, a mitochondrial enzyme responsible for metabolizing the major lipid peroxidation product, protects against acute ischemia/reperfusion injury and chronic heart failure。 Activation of ALDH2, the main enzyme that catalyzes 4-HNE metabolism, is sufficient to protect the heart against acute ischemia-reperfusion injury。

ALDH2 is a key detoxifying enzyme。 ALDH2 is most commonly associated with its role in ethanol metabolism, catalyzing the oxidation of ethanol-derived acetaldehyde to acetate。

Aldehyde Dehydrogenase (ALDH) 相关产品 (5):

Cat. No. Product Name Effect Purity
  • HY-B0240
    Disulfiram Inhibitor 98.67%
    Disulfiram 是特异性的乙醛脱氢酶1型抗体 (ALDH1) 抑制剂,可以通过对酒精产生急性敏感性来治疗慢性酗酒。
  • HY-18936
    Alda-1 Agonist 99.81%
    Alda-1是有效的 ALDH2 激动剂,其激活野生型ALDH2并恢复近似野生型活性至ALDH2*2。
  • HY-18768
    NCT-501 Inhibitor 99.78%
    NCT-501是一种茶碱类的有效醛脱氢酶1A1 (ALDH1A1) 选择性抑制剂, 抑制hALDH1A1时IC50值为40 nM, 选择性超过其它ALDH同工酶和其它脱氢酶 (作用于hALDH1B1, hALDH3A1, 和hALDH2时, IC50值 >57 UM)。
  • HY-112277
    NCT-505 Inhibitor
    NCT-505 是一种有效的,选择性的乙醛脱氢酶 (aldehyde dehydrogenase (ALDH1A1)) 抑制剂,IC50 值为 7 nM,对 hALDH1A2,hALDH1A3,hALDH2,hALDH3A1 的抑制作用较弱,IC50 值分别为 >57,22.8,20.1,>57 μM。
  • HY-112278
    NCT-506 Inhibitor
    NCT-506 是一种口服生物可利用的醛脱氢酶 1A1 (ALDH1A1) 抑制剂,IC50 为 7 nM。
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately。

天娱彩票 天娱彩票 博乐彩票 完美彩票 博乐彩票 博乐彩票 同城彩票 博乐彩票 王者彩票 王者彩票