AZD-0284 

目录号: HY-120384
产品使用指南

AZD-0284是核受体 RORγ 的反向激动剂。 在开发用于治疗寻常型斑块状银屑病和呼吸道疾病。

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AZD-0284 Chemical Structure

AZD-0284 Chemical Structure

CAS No. : 2101291-07-8

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Description

AZD-0284 is an inverse agonist of the nuclear receptor RORγ. In development for the treatment of plaque psoriasis vulgaris and respiratory tract disorders[1].

IC50 & Target

RORγ[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9068 mL 9.5342 mL 19.0683 mL
5 mM 0.3814 mL 1.9068 mL 3.8137 mL
10 mM 0.1907 mL 0.9534 mL 1.9068 mL
*Please refer to the solubility information to select the appropriate solvent.
References
  • [1].

Molecular Weight

524.43

Formula

C₂₁H₁₈F₆N₂O₅S

CAS No.

2101291-07-8

SMILES

O=C([C@@H]1N(C(C)=O)CC2=C1C=CC(S(=O)(C)=O)=C2)NC3=CC=C(C(C(F)(F)F)(O)C(F)(F)F)C=C3

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • [1].

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Inquiry Information

产品名称:
AZD-0284
目录号:
HY-120384
需求量:

AZD-0284

Cat. No.: HY-120384

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